LSV Seminar

The LSV seminar takes place on Tuesday at 11:00 AM. The usual location is the conference room at Pavillon des Jardins (venue). If you wish to be informed by e-mail about upcoming seminars, please contact Stéphane Le Roux and Matthias Fuegger.

The seminar is open to public and does not require any form of registration.

Past Seminars

BioModel Engineering - a Petri Net Perspective

 Monika Heiner
Tuesday, October 01 2013 at 11:00AM
Salle de Conférence (Pavillon des Jardins)
Monika Heiner (Brandenburg University of Technology at Cottbus)

The talk describes a Petri net-based framework to model and analyse biochemical networks, such as gene regulatory, signal transduction or metabolic networks. The framework comprises the qualitative, stochastic, and continuous modelling paradigms.

Each perspective adds its contribution to the better understanding of the biochemical system under study. This will be illustrated by two examples showing how structural analysis techniques, specifically Petri net T-invariants, may be of help.

First, a technique is discussed supporting modularisation and hierarchical representation of a given network by network coarsening. Second, a case study is presented where structural analysis helps to identify the core network and fragile nodes of a continuous network in the steady-state interpretation.

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